Spakowski M, Nikolic N, Giambarba C [Ethanol, water, salt and coma.] [English Abstract, Journal Article] Praxis (Bern 1994) 2009 Aug 12; 98(16):905-8.
We report on a 52-year-old woman with liver cirrhosis who suddenly fell into deep coma after correction of an intercurrent hyponatremia. After exclusion of the commonest causes of coma, the MRI showed a symmetrical osmotic demyelination of both thalami. The newest epidemiological data, the pathyophysiology of osmotic demyelination, the threats of the treatment of a prolonged severe hyponatremia as well as the therapeutic options in face of osmotic demyelination are discussed.
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